Our multivariate logistic regression analysis showed that obesity, diabetes, coronary heart disease, cerebrovascular disease and chronic kidney disease were independent risk factors associated with BP target attainment failure. 9%) in our hypertensive dyslipidemia patients. For those with diabetes, CHD and/or CKD, the lower BP target (< mmHg) in the 2010 Chinese Hypertension Guideline may partially account for the disappointing BP attainment rates. However, the BP target rate in patients with obesity or cerebrovascular disease were also very low, though these patients shared the same BP target value (SBP/DBP < mmHg) as uncomplicated hypertensives. Moreover, the analysis of dyslipidemia management in DYSIS-China also revealed that diabetes was a strong predictor of failure in attaining LDL-C and non-HDL-C goals . Zhao's result are in accordance with the findings of our multivariate logistic regression analysis, which showed that diabetes was an independent risk factor for not achieving BP and combined BP and LDL-C targets. Therefore, besides the stricter BP target value for these comorbidities, there must be other reasons (vide supra) that may account for the low BP target attainment rates. Further measures should be taken to spread the recommendations of our guidelines in order to improve BP and LDL-C control rate in patients with comorbidities. The doctors in endocrine or neurology departments should focus more on the control of BP and LDL-C in their patients, though the circumstances in other departments were also not optimal in our study.
Whether or not in the “Most other Divisions” the brand new percentages of managed patients (55.9% to have blood pressure and you may 62.4% having lipid minimizing pills) was not the highest (Extra document step 1: Desk S1), the prospective attainment prices getting BP (43.4%) (Extra file 2: Table S2), LDL-C (68%) (Table dos) and both BP and you may LDL-C (thirty-five.5%) (Extra file step 3: Table S3) was in fact the highest among the departments tested. A potential factor could well be that for the “Almost every other Departments” the new prevalence off comorbidities and you will risk activities were lower and you can less people needed seriously to has actually its BP and you will LDL-C less than mmHg and you can 2.0 mmol/L, correspondingly.
Today’s investigation has several constraints. Because is a keen observational get across-sectional studies, long-name effects cannot getting examined. Concurrently, the information of the patients’ conformity wasn’t obtained purposefully when you look at the DYSIS-Asia. And therefore we could not learn the newest patients’ adherence to cures precisely in the present data. Furthermore, every customers signed up for DYSIS-Asia had already received at the least 3 months antidyslipidemia treatment (addition standards to own DYSIS-China) as well as the procedures rates regarding statins in this diligent people was as much as 89.7%. In the event the DYSIS-China could have signed up dyslipidemia sufferers repeatedly and not got rid of clients versus early in the day antidyslipidemia treatment, the fresh new statins’ therapy price would have certainly been lower than 89.7%, and combined BP and you can LDL-C targets attainment cost bad than others in the modern research.
While the incidence regarding hypertension for the Chinese dyslipidemia patients are large, a considerable ratio out of clients failed to achieve the BP target, plus both BP and you will LDL-C aim. An incomplete management system, incorrect monotherapy, improper diuretic drug and bad therapy conformity may take into account the fresh new unsatisfactory objective attainment rates within the Chinese people that have both hypertension and you can dyslipidemia. The data from our study certainly advise that the new establishment off an audio government system for the treatment of hypertension and dyslipidemia will be feel a significant medical care strategy in the China.
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Zhang Meters, Deng Q, Wang L, Huang Z, Zhou M, Li Y, Zhao Z, Zhang Y, Wang L. Frequency of dyslipidemia and you may end regarding reasonable-density lipoprotein cholesterol purpose for the Chinese grownups: a nationally associate survey away from 163,641 adults. Int J Cardiol. 2018;–203.